So as soon as I select "OC manually" in literally any X470/X570 BIOS, it's like TDP doesn't exist? If the goal is highest single core overclock, you'd prefer chips with lower TDP/core ratio since that usually means the cores are better binned?
Once you overclock (either manually or automatically) the TDP of the chip increases above the stock value and you need better cooling system to dissipate the heat from the chip. E.g. a chip can have a TDP of 95W on stock clocks and a TDP of 210W when overclocked. Wait to actual chips to be released to see how is AMD binning each SKU, which is silicon variability within the seam SKU, and what chip has better silicon for what you want to do. No one can answer that now.
High TDP with fewer cores doesn't imply better OC headroom. It can mean that those SKUs are using worse silicon and need higher TDP to achieve similar clocks than SKUs on better silicon.