I had a T5810 MB die in the Pent. It was running an E5-2698V4 and 4 RTX 3070Ti's on it. Pulled the Xeon and put it into service in an x99 board and repurposed an old x58 w/ an i7 920 for the GPU's.
I'll add that if you are running an instance and max it out at ~1,000 WU's and it completes before you want to turn on networking you can start a second or third, etc., and run the same project adding another 1,000 units each.
For those of you with fast gaming machines who want to contribute...
Super simple to set up multiple instances. You can load up one with GPU work and turn off the network to that one instance while loading up another with CPU work on another project and control the network activity separately on that instance...
Borderlands 2 was one of the toughest physx titles I can remember. Pretty sure there was a lack of optimization or something just hammering the GPU's. I remember adding a 750ti to a pair of sli'd 780ti's to take the physx stress off the GPU the last time I played around with that title ~2014or...